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ChemVerify

SNAP-8

Anti-Aging
1075.2 Da
Research Chemical - Not for Human Use

Quick Facts

Category
Anti-Aging
Molecular Weight
1075.2 Da
CAS Number
868844-74-0
Amino Acids
8
Storage
Store lyophilized at -20°C.
Solubility
Soluble in water

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Description

SNAP-8 (Acetyl Octapeptide-3) is a synthetic octapeptide that mimics the N-terminal end of SNAP-25, a substrate of the SNARE complex. It is investigated for its effects on neuromuscular junction signaling and muscle contraction. Research applications include studies of exocytosis mechanisms and cellular communication.

Research Summary

SNAP-8 has been investigated in dermatological research for its effects on neuromuscular junction signaling. In vitro studies demonstrate inhibition of SNARE complex formation and reduction of catecholamine release from chromaffin cells. Research applications focus on understanding exocytosis mechanisms at the cellular level.

Mechanism of Action

Competes with native SNAP-25 for positions in the SNARE complex, a protein assembly essential for synaptic vesicle fusion and neurotransmitter release. By reducing functional SNARE complex formation, it decreases the frequency of neuromuscular signaling events.

Known Research Compound Interactions

Based on published preclinical research literature

mg
mL

For laboratory research use only. Not for human consumption.